BIOL6339 - Regulation of Eukaryotic Protein Synthesis

BIOL 6339 Regulation of Eukaryotic Protein Synthesis (3 semester credit hours) This course will focus on how mRNAs are decoded by ribosomes to produce proteins in cells. The course will discuss insights from model organisms, cancer, neurodegeneration, learning, and memory. Topics will cover a range of mechanisms spanning editing, programmed frame-shifting, cap-dependent and independent scanning, elongation, the integrated stress response, termination, recycling, rescue, and collision resolution. The course will consist of lectures, presentations of journal articles, guest lectures, and group discussions. As a capstone to the course, students will produce a brief research proposal related to a topic visited in the course. Department consent required. (3-0) R