Master of Science in Bioinformatics and Computational Biology
36 semester credit hours minimum
Mathematics Faculty
Professors: Larry P. Ammann , Zalman I. Balanov , Swati Biswas , Pankaj K. Choudhary , Mieczyslaw K. Dabkowski , Vladimir Dragovic , Sam Efromovich , Yulia Gel , M. Ali Hooshyar , Wieslaw Krawcewicz , Susan E. Minkoff , L. Felipe Pereira , Dmitry Rachinskiy , Viswanath Ramakrishna , Janos Turi , John Zweck
Professors Emeritus: Patrick Odell , John W. Van Ness
Clinical Professors: Natalia Humphreys , Wenyi (Roy) Lu
Associate Professors: Yan Cao , Min Chen
Clinical Associate Professor: Mohammad Akbar
Assistant Professors: Maxim Arnold , Carlos Arreche , Bhargab Chattopadhyay , Sy Han (Steven) Chiou , Qingwen Hu , Frank Konietschke , Yifei Lou , Oleg Makarenkov , Tomoki Ohsawa , Sunyoung Shin , Anh Tran , Nathan Williams
Associate Professor of Instruction: My Linh Nguyen
Senior Lecturers: Mohammad Ahsan , Kelly Aman , Malgorzata Dabkowska , Rabin Dahal , Anatoly Eydelzon , Manjula Foley , Bentley T. Garrett , Yuly Koshevnik , David L. Lewis , Changsong Li , Brady McCary , Derege Mussa , Paul Stanford , Julie Sutton , Tristan Whalen
UT Dallas Affiliated Faculty: Hervé Abdi , Titu Andreescu , Alain Bensoussan , Stefano Leonardi , Faruck Morcos , Zhenyu Xuan , Hyuntae Yoo , Michael Qiwei Zhang
Mathematics Faculty With Research Interests in Bioinformatics and Computational Biology: Swati Biswas, Yan Cao, and Min Chen
Biology Faculty
Professors: Lee A. Bulla , Rockford K. Draper , Juan E. González , Lawrence J. Reitzer , Stephen Spiro , Li Zhang , Michael Qiwei Zhang
Professors Emeritus: Hans Bremer , Donald M. Gray
Clinical Professor: David Murchison
Associate Professors: Gail A. M. Breen , John G. Burr , Jeff L. DeJong , Heng Du , Ernest M. Hannig , Tae Hoon Kim , Dennis L. Miller , Kelli Palmer , Duane D. Winkler , Zhenyu Xuan
Assistant Professors: Zachary Campbell , Nikki Delk , Jung-whan (Jay) Kim , Faruck Morcos , Hyuntae Yoo
Research Assistant Professors: Lan Guo , Li Liu
Senior Lecturers: Irina Borovkov , Mehmet Candas , Brenna Hill , Wen-Ju Lin , Meenakshi Maitra , Robert C. Marsh , Jing Pan , Elizabeth Pickett , Ruben D. Ramirez , Scott A. Rippel , Ilya Sapozhnikov , Uma Srikanth , Michelle Wilson , Wen-Ho Yu
UT Dallas Affiliated Faculty: Leonidas Bleris , Sheena D'Arcy , Stephen D. Levene , Jonathan E. Ploski , Lucien (Tres) Thompson
Biological Sciences Faculty With Research Interests in Bioinformatics and Computational Biology: Faruck Morcos, Zhenyu Xuan, Hyuntae Yoo, and Michael Q. Zhang
Program Objective
The Master of Science program in Bioinformatics and Computational Biology is an interdisciplinary program offered jointly by the Departments of Mathematical Sciences and Biological Sciences, with the former serving as the administrative unit. By combining coursework from the disciplines of Biology, Computer Science, Mathematics, and Statistics, it caters to the growing demand of a new breed of scientists who have expertise in all these disciplines. In addition to coursework, the program also provides opportunities to gain practical experience by getting involved in research with faculty members.
A successful applicant to the program is expected to have a Bachelor's degree in Biology, Mathematics, Statistics, or in another science/engineering discipline, and must have completed Differential and Integral Calculus courses. Additional coursework in one or more of the disciplines of Biology, Computer Science, Mathematics, and Statistics is desirable but is not required.
Degree Requirements
The University's general degree requirements are discussed on the Graduate Policies and Procedures page.
The MS program in Bioinformatics and Computational Biology requires completion of at least 36 semester credit hours. The program offers a choice between two tracks. Track 1 is designed for students with a general background in science/engineering, whereas Track 2 is designed for students with a strong background in biology. To build further expertise, both tracks offer a choice of three elective groups, namely, Computer Science oriented, Statistics oriented, and Biology oriented elective groups. Both also offer opportunities for research. Students are expected to choose a track and an elective group based on their backgrounds and interests in consultation with the Graduate Advisor for the program.
Track 1 (MS)
I. Core: 15 semester credit hours
BMEN 6374 Genes, Proteins and Cell Biology for Engineers
BIOL 6V00 Topics in Biological Sciences (Computational Molecular Evolution)
CS 5303 Computer Science I
MATH 5303 Advanced Calculus and Linear Algebra
STAT 5351 Probability and Statistics I (for Elective Group 2)
or STAT 5353 Probability and Statistics for Data Science and Bioinformatics (for Elective Groups 1 and 3)
II. Elective Groups (Choose one elective group)
Elective Group 1 (Computer Science Oriented): 15 semester credit hours
CS 5343 Algorithm Analysis and Data Structures1
MATH 6312 Combinatorics and Graph Theory
MATH 6341 Bioinformatics
or BIOL 5376 Applied Bioinformatics
MATH 6346 Medical Image Analysis
AND one of the following:
CS 6307 Introduction to Big Data Management and Analytics for non-CS Majors
CS 6314 Web Programming Languages
CS 6360 Database Design
CS 6375 Machine Learning
Elective Group 2 (Statistics Oriented): 18 semester credit hours
STAT 5352 Probability and Statistics II
STAT 6337 Advanced Statistical Methods I
STAT 6338 Advanced Statistical Methods II
STAT 6340 Statistical and Machine Learning
MATH 6341 Bioinformatics
or BIOL 5376 Applied Bioinformatics
MATH 6346 Medical Image Analysis
Elective Group 3 (Biology oriented): 15 semester credit hours
MATH 6341 Bioinformatics
or BIOL 5376 Applied Bioinformatics
MATH 6345 Mathematical Methods in Medicine and Biology
MATH 6346 Medical Image Analysis
AND two of the following:
BIOL 5375 Genes to Genomes
BIOL 5381 Genomics
BIOL 6315 Epigenetics
BIOL 6373 Proteomics
BIOL 6385 Computational Biology
or BMEN 6389 Computational Biology
or MATH 6343 Computational Biology
III. Research or Elective(s) or a Combination Thereof
- Elective Group 1: 6 semester credit hours
- Elective Group 2: 3 semester credit hours
- Elective Group 3: 6 semester credit hours
Track 2 (MS)
I. Core: 14 semester credit hours
BIOL 5410 Biochemistry
BIOL 5420 Molecular Biology
STAT 5351 Probability and Statistics I (for Elective Group 2)
or STAT 5353 Probability and Statistics for Data Science and Bioinformatics (for Elective Groups 1 and 3)
MATH 5303 Advanced Calculus and Linear Algebra
II. Elective Groups (Choose one elective group)
Elective Group 1 (Computer Science oriented): 18 semester credit hours
CS 5303 Computer Science I
CS 5343 Algorithm Analysis and Data Structures1
MATH 6312 Combinatorics and Graph Theory
MATH 6341 Bioinformatics
or BIOL 5376 Applied Bioinformatics
MATH 6346 Medical Image Analysis
AND one of the following:
CS 6307 Introduction to Big Data Management and Analytics for non-CS Majors
CS 6314 Web Programming Languages
CS 6360 Database Design
CS 6375 Machine Learning
Elective Group 2 (Statistics oriented): 18 semester credit hours
STAT 5352 Probability and Statistics II
STAT 6337 Advanced Statistical Methods I
STAT 6338 Advanced Statistical Methods II
STAT 6340 Statistical and Machine Learning
MATH 6341 Bioinformatics
or BIOL 5376 Applied Bioinformatics
MATH 6346 Medical Image Analysis
Elective Group 3 (Biology oriented): At least 18 semester credit hours
MATH 6341 Bioinformatics
or BIOL 5376 Applied Bioinformatics
MATH 6346 Medical Image Analysis
MATH 6345 Mathematical Methods in Medicine and Biology
3 semester credit hour Elective Course
AND two of the following:
BIOL 5375 Genes to Genomes
BIOL 5381 Genomics
BIOL 6315 Epigenetics
BIOL 6373 Proteomics
BIOL 6385 Computational Biology
or BMEN 6389 Computational Biology
or MATH 6343 Computational Biology
BIOL 6V00 Topics in Biological Sciences (Computational Molecular Evolution)
BIOL 6V00 Topics in Biological Sciences (Introduction to Programming for Biological Sciences)
III. Research or Elective(s) or a Combination Thereof
All Elective Groups: 4 semester credit hours
Other Requirements
- For a PhD bound student in the Department of Biological Sciences, BIOL 5440 Cell Biology and BIOL 5460 Quantitative Biology (or an equivalent) are required. This requirement can be fulfilled by taking these courses as 'electives' in the Bioinformatics and Computational Biology program.
- Electives must be approved by the Graduate Advisor of the program.
- Substitutions for required courses may be made if approved by the Graduate Advisor of the program and the Head of the Mathematical Sciences Department.
- A student may choose to write an MS thesis under the supervision of a faculty member. The thesis project can count for 3 to 6 semester credit hours of electives towards the required 36 hours, in accordance with University policies. The thesis must be approved by the Head of the Mathematical Sciences Department. Once the thesis project is completed, the student must successfully defend it before his/her thesis committee.
1. Students who have not taken the CS 5333 Discrete Structures prerequisite for CS 5343 Algorithm Analysis and Data Structures should consult with their Graduate Advisor from the Mathematical Sciences Department to determine eligibility.