BIOL6V59 - Comparative Analysis of Genes and Proteins

BIOL 6V59 Comparative Analysis of Genes and Proteins (2-5 semester credit hours) This self-guided study focuses on proteins' diverse properties, aiming to equip students with bioinformatics and AI tools to explore protein structures and functions. Projects integrate alignment, clustering, structure modeling, and virtual screening to evaluate molecular features. Studies include identifying sequence motifs, analyzing conserved domains, visualizing 3D structures, classifying unstructured regions, constructing phylogenetic profiles, speculating on mutation effects, and interpreting physicochemical descriptors in ligand binding, enzyme catalysis, protein interactions, and drug action. Students need a foundational understanding of protein biochemistry and biological databases. Instructor consent required. ([2-5]-0) Y